4TR9
Ternary co-crystal structure of fructose-bisphosphate aldolase from Plasmodium falciparum in complex with TRAP and a small molecule inhibitor
Summary for 4TR9
Entry DOI | 10.2210/pdb4tr9/pdb |
Related | 2pc4 |
Descriptor | Fructose-bisphosphate aldolase, ALA-ALA-SER-LEU-TYR-GLU-LYS-LYS-ALA-ALA, ALA-ALA-ALA-SER-LEU-TYR-GLU-LYS-LYS-ALA-ALA, ... (6 entities in total) |
Functional Keywords | lyase-lyase inhibitor complex, lyase/lyase inhibitor |
Biological source | Plasmodium falciparum More |
Total number of polymer chains | 10 |
Total formula weight | 165823.37 |
Authors | Bosch, G.,Weltzer, R.,O'Malley, K.,Bosch, J. (deposition date: 2014-06-15, release date: 2015-08-26, Last modification date: 2023-09-27) |
Primary citation | Nemetski, S.M.,Cardozo, T.J.,Bosch, G.,Weltzer, R.,O'Malley, K.,Ejigiri, I.,Kumar, K.A.,Buscaglia, C.A.,Nussenzweig, V.,Sinnis, P.,Levitskaya, J.,Bosch, J. Inhibition by stabilization: targeting the Plasmodium falciparum aldolase-TRAP complex. Malar.J., 14:324-324, 2015 Cited by PubMed: 26289816DOI: 10.1186/s12936-015-0834-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.111 Å) |
Structure validation
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