4TR9

Ternary co-crystal structure of fructose-bisphosphate aldolase from Plasmodium falciparum in complex with TRAP and a small molecule inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Fructose-bisphosphate aldolase	polymer	369	40152.9	4	UniProt (Q7KQL9) Pfam (PF00274) In PDB	Plasmodium falciparum
2	E	ALA-ALA-SER-LEU-TYR-GLU-LYS-LYS-ALA-ALA	polymer	10	1053.2	1	UniProt (by SIFTS) (Q7KQL9) In PDB	Plasmodium falciparum 3D7
3	G	ALA-ALA-ALA-SER-LEU-TYR-GLU-LYS-LYS-ALA-ALA	polymer	11	1124.3	1	UniProt (by SIFTS) (Q7KQL9) In PDB	Plasmodium falciparum 3D7
4	H, I, J, K	ASP-TRP-ASN	polymer	3	433.4	4	UniProt (by SIFTS) (Q76NM2) In PDB	Plasmodium falciparum 3D7
5	A, B, C, K	N'-[(E)-(2,4-dichlorophenyl)methylidene]-3,4-dihydroxybenzohydrazide	non-polymer		325.1	4	Chemie (38D)
6		water	water		18.0	604	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	164522.8
Non-Polymers*	Number of molecules	4
	Total formula weight	1300.6
All*	Total formula weight	165823.4

*Water molecules are not included.