4TR9
Ternary co-crystal structure of fructose-bisphosphate aldolase from Plasmodium falciparum in complex with TRAP and a small molecule inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Fructose-bisphosphate aldolase | polymer | 369 | 40152.9 | 4 | UniProt (Q7KQL9) Pfam (PF00274) | Plasmodium falciparum | |
| 2 | E (E) | ALA-ALA-SER-LEU-TYR-GLU-LYS-LYS-ALA-ALA | polymer | 10 | 1053.2 | 1 | UniProt (by SIFTS) (Q7KQL9) | Plasmodium falciparum 3D7 | |
| 3 | F (G) | ALA-ALA-ALA-SER-LEU-TYR-GLU-LYS-LYS-ALA-ALA | polymer | 11 | 1124.3 | 1 | UniProt (by SIFTS) (Q7KQL9) | Plasmodium falciparum 3D7 | |
| 4 | G, H, I, J (H, I, J, K) | ASP-TRP-ASN | polymer | 3 | 433.4 | 4 | UniProt (by SIFTS) (Q76NM2) | Plasmodium falciparum 3D7 | |
| 5 | K, L, M, N (A, B, C, K) | N'-[(E)-(2,4-dichlorophenyl)methylidene]-3,4-dihydroxybenzohydrazide | non-polymer | 325.1 | 4 | Chemie (38D) PubChem (707940) PubChem (5396179) PubChem (5332252) | |||
| 6 | O, P, Q, R, S... (A, B, C, D, E...) | water | water | 18.0 | 604 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 164522.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1300.6 | |
| All* | Total formula weight | 165823.4 |
