4TN3
Structure of the BBox-Coiled-coil region of Rhesus Trim5alpha
Summary for 4TN3
| Entry DOI | 10.2210/pdb4tn3/pdb |
| Descriptor | TRIM5/cyclophilin A fusion protein/T4 Lysozyme chimera, ZINC ION (2 entities in total) |
| Functional Keywords | trim protein coiled-coil scaffold retroviral restriction factor, antiviral protein |
| Biological source | Macaca mulatta (Rhesus macaque) More |
| Total number of polymer chains | 2 |
| Total formula weight | 92931.19 |
| Authors | Kirkpatrick, J.J.,Stoye, J.P.,Taylor, I.A.,Goldstone, D.C. (deposition date: 2014-06-03, release date: 2014-07-16, Last modification date: 2023-09-27) |
| Primary citation | Goldstone, D.C.,Walker, P.A.,Calder, L.J.,Coombs, P.J.,Kirkpatrick, J.,Ball, N.J.,Hilditch, L.,Yap, M.W.,Rosenthal, P.B.,Stoye, J.P.,Taylor, I.A. Structural studies of postentry restriction factors reveal antiparallel dimers that enable avid binding to the HIV-1 capsid lattice. Proc.Natl.Acad.Sci.USA, 111:9609-9614, 2014 Cited by PubMed: 24979782DOI: 10.1073/pnas.1402448111 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.1989 Å) |
Structure validation
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