4TN3

Structure of the BBox-Coiled-coil region of Rhesus Trim5alpha

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	TRIM5/cyclophilin A fusion protein/T4 Lysozyme chimera	polymer	400	46334.8	2	UniProt (G9MAP5) UniProt (P00720) Pfam (PF00643) Pfam (PF00959) In PDB	Macaca mulatta (Rhesus macaque)	Lysis protein,Lysozyme,Muramidase
2	A, B	ZINC ION	non-polymer		65.4	4	Chemie (ZN)

Sequence modifications

A, B: 88 - 303 (UniProt: G9MAP5)

PDB	External Database	Details
Met 68	-	expression tag
Ala 69	-	expression tag
His 70	-	expression tag
His 71	-	expression tag
His 72	-	expression tag
His 73	-	expression tag
His 74	-	expression tag
His 75	-	expression tag
Ser 76	-	expression tag
Ala 77	-	expression tag
Ala 78	-	expression tag
Leu 79	-	expression tag
Glu 80	-	expression tag
Val 81	-	expression tag
Leu 82	-	expression tag
Phe 83	-	expression tag
Gln 84	-	expression tag
Gly 85	-	expression tag
Pro 86	-	expression tag
Gly 87	-	expression tag

A, B: 304 - 467 (UniProt: P00720)

PDB	External Database	Details
Gly 315	Arg 12	conflict
Asn 323	Asp 20	conflict
Thr 357	Cys 54	conflict
Ala 400	Cys 97	conflict
Arg 440	Ile 137	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	92669.6
Non-Polymers*	Number of molecules	4
	Total formula weight	261.6
All*	Total formula weight	92931.2

*Water molecules are not included.