4S2C

Covalent complex of E. coli transaldolase TalB with fructose-6-phosphate

Summary for 4S2C

Entry DOI	10.2210/pdb4s2c/pdb
Related	1ONR 3CWN 4RZ5 4RZ6 4S2B
Descriptor	Transaldolase B, FRUCTOSE -6-PHOSPHATE, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	tim barrel, pentose phosphate pathway, schiff base fructose 6-phosphate, transferase
Biological source	Escherichia coli K-12
Cellular location	Cytoplasm : P0A870
Total number of polymer chains	2
Total formula weight	75501.46
Authors	Stellmacher, L.,Sandalova, T.,Schneider, G.,Sprenger, G.A.,Samland, A.K. (deposition date: 2015-01-20, release date: 2016-01-20, Last modification date: 2023-09-20)
Primary citation	Stellmacher, L.,Sandalova, T.,Schneider, S.,Schneider, G.,Sprenger, G.A.,Samland, A.K. Novel mode of inhibition by D-tagatose 6-phosphate through a Heyns rearrangement in the active site of transaldolase B variants. Acta Crystallogr D Struct Biol, 72:467-476, 2016 Cited by PubMed: 27050126 DOI: 10.1107/S2059798316001170 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation