4S1T

Crystal structure of the mutant I26A/N52A of the endoribonuclease from human coronavirus 229E

4S1T の概要

• エントリーDOI: 10.2210/pdb4s1t/pdb
• 分子名称: Uridylate-specific endoribonuclease, PHOSPHATE ION (3 entities in total)
• 機能のキーワード: hcov-229e, endoribonuclease, trimeric nsp15, double mutation, hydrolase
• 由来する生物種: Human coronavirus 229E (HCoV-229E)
• 細胞内の位置: Non-structural protein 3: Host membrane ; Multi-pass membrane protein . Non-structural protein 4: Host membrane ; Multi-pass membrane protein . Non-structural protein 6: Host membrane ; Multi-pass membrane protein . Non-structural protein 7: Host cytoplasm, host perinuclear region . Non-structural protein 8: Host cytoplasm, host perinuclear region . Non-structural protein 9: Host cytoplasm, host perinuclear region . Non-structural protein 10: Host cytoplasm, host perinuclear region . Helicase: Host endoplasmic reticulum-Golgi intermediate compartment . Uridylate-specific endoribonuclease: Host cytoplasm, host perinuclear region : P0C6X1
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 233503.23

構造登録者

Huo, T.,Liu, X. (登録日: 2015-01-15, 公開日: 2016-01-20, 最終更新日: 2023-11-08)

• 主引用文献: Huo, T.,Liu, X.,Yang, C.,Rao, Z.; Crystal structure and mutational analysis of the endoribonuclease from human coronavirus 229E; To be Published,

実験手法

X-RAY DIFFRACTION (2.504 Å)