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4RZS

Lac repressor engineered to bind sucralose, unliganded tetramer

Summary for 4RZS
Entry DOI10.2210/pdb4rzs/pdb
DescriptorLac repressor, GLYCEROL (3 entities in total)
Functional Keywordssucralose, laci, lac repressor, lactose operon repressor, protein design, allostery, escherichia coli, transcription
Biological sourceEscherichia coli
Total number of polymer chains4
Total formula weight163902.33
Authors
Arbing, M.A.,Cascio, D.,Kosuri, S.,Church, G.M. (deposition date: 2014-12-24, release date: 2015-12-23, Last modification date: 2024-02-28)
Primary citationTaylor, N.D.,Garruss, A.S.,Moretti, R.,Chan, S.,Arbing, M.A.,Cascio, D.,Rogers, J.K.,Isaacs, F.J.,Kosuri, S.,Baker, D.,Fields, S.,Church, G.M.,Raman, S.
Engineering an allosteric transcription factor to respond to new ligands.
Nat.Methods, 13:177-183, 2016
Cited by
PubMed: 26689263
DOI: 10.1038/nmeth.3696
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.71 Å)
Structure validation

217705

건을2024-03-27부터공개중

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