4RZS
Lac repressor engineered to bind sucralose, unliganded tetramer
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Lac repressor | polymer | 381 | 40883.5 | 4 | UniProt (C9QQT3) Pfam (PF00356) Pfam (PF13377) UniProt (by SIFTS) (P03023) In PDB | Escherichia coli | Transcriptional regulator, LacI family |
2 | A, B, C, D | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
3 | water | water | 18.0 | 23 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 360 (UniProt: C9QQT3)
PDB | External Database | Details |
---|---|---|
Met -20 | - | expression tag |
Gly -19 | - | expression tag |
Ser -18 | - | expression tag |
Ser -17 | - | expression tag |
His -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
Ser -10 | - | expression tag |
Ser -9 | - | expression tag |
Gly -8 | - | expression tag |
Leu -7 | - | expression tag |
Val -6 | - | expression tag |
Pro -5 | - | expression tag |
Arg -4 | - | expression tag |
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
His -1 | - | expression tag |
Met 0 | - | expression tag |
Thr 149 | Asp 152 | engineered mutation |
Ala 150 | Val 153 | engineered mutation |
Leu 156 | Ile 159 | engineered mutation |
Asp 193 | Ser 196 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 163534.0 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 368.4 | |
All* | Total formula weight | 163902.3 |