4RWF
Crystal structure of the CLR:RAMP2 extracellular domain heterodimer with bound adrenomedullin
Summary for 4RWF
Entry DOI | 10.2210/pdb4rwf/pdb |
Related | 4RWG |
Related PRD ID | PRD_900001 |
Descriptor | Maltose transporter subunit, Receptor activity-modifying protein 2, Calcitonin gene-related peptide type 1 receptor fusion protein, Adrenomedullin, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | cell surface receptor, membrane protein-hormone complex, membrane protein/hormone |
Biological source | Escherichia coli (human) More |
Total number of polymer chains | 2 |
Total formula weight | 70213.65 |
Authors | Booe, J.,Pioszak, A. (deposition date: 2014-12-03, release date: 2015-05-20, Last modification date: 2020-07-29) |
Primary citation | Booe, J.M.,Walker, C.S.,Barwell, J.,Kuteyi, G.,Simms, J.,Jamaluddin, M.A.,Warner, M.L.,Bill, R.M.,Harris, P.W.,Brimble, M.A.,Poyner, D.R.,Hay, D.L.,Pioszak, A.A. Structural Basis for Receptor Activity-Modifying Protein-Dependent Selective Peptide Recognition by a G Protein-Coupled Receptor. Mol.Cell, 58:1-13, 2015 Cited by PubMed: 25982113DOI: 10.1016/j.molcel.2015.04.018 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.76 Å) |
Structure validation
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