4RPI
Crystal Structure of Nicotinate Mononucleotide Adenylyltransferase from Mycobacterium tuberculosis
Summary for 4RPI
| Entry DOI | 10.2210/pdb4rpi/pdb |
| Descriptor | nicotinate-nucleotide adenylyltransferase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, ... (4 entities in total) |
| Functional Keywords | nadd, nad biosynthesis, transferase |
| Biological source | Mycobacterium tuberculosis |
| Total number of polymer chains | 4 |
| Total formula weight | 98249.50 |
| Authors | Rodionova, I.,Zuccola, H.,Sorci, L.,Aleshin, A.E.,Kazanov, M.,Sergienko, E.,Rubin, E.,Locher, C.,Osterman, A. (deposition date: 2014-10-30, release date: 2015-01-28, Last modification date: 2024-02-28) |
| Primary citation | Rodionova, I.A.,Zuccola, H.J.,Sorci, L.,Aleshin, A.E.,Kazanov, M.D.,Ma, C.T.,Sergienko, E.,Rubin, E.J.,Locher, C.P.,Osterman, A.L. Mycobacterial nicotinate mononucleotide adenylyltransferase: structure, mechanism, and implications for drug discovery. J. Biol. Chem., 290:7693-7706, 2015 Cited by PubMed: 25631047DOI: 10.1074/jbc.M114.628016 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.417 Å) |
Structure validation
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