4RPI

Crystal Structure of Nicotinate Mononucleotide Adenylyltransferase from Mycobacterium tuberculosis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000309	molecular_function	nicotinamide-nucleotide adenylyltransferase activity
A	0003824	molecular_function	catalytic activity
A	0004515	molecular_function	nicotinate-nucleotide adenylyltransferase activity
A	0005524	molecular_function	ATP binding
A	0009058	biological_process	biosynthetic process
A	0009165	biological_process	nucleotide biosynthetic process
A	0009435	biological_process	NAD biosynthetic process
A	0016779	molecular_function	nucleotidyltransferase activity
A	0019363	biological_process	pyridine nucleotide biosynthetic process
A	0070566	molecular_function	adenylyltransferase activity
B	0000309	molecular_function	nicotinamide-nucleotide adenylyltransferase activity
B	0003824	molecular_function	catalytic activity
B	0004515	molecular_function	nicotinate-nucleotide adenylyltransferase activity
B	0005524	molecular_function	ATP binding
B	0009058	biological_process	biosynthetic process
B	0009165	biological_process	nucleotide biosynthetic process
B	0009435	biological_process	NAD biosynthetic process
B	0016779	molecular_function	nucleotidyltransferase activity
B	0019363	biological_process	pyridine nucleotide biosynthetic process
B	0070566	molecular_function	adenylyltransferase activity
C	0000309	molecular_function	nicotinamide-nucleotide adenylyltransferase activity
C	0003824	molecular_function	catalytic activity
C	0004515	molecular_function	nicotinate-nucleotide adenylyltransferase activity
C	0005524	molecular_function	ATP binding
C	0009058	biological_process	biosynthetic process
C	0009165	biological_process	nucleotide biosynthetic process
C	0009435	biological_process	NAD biosynthetic process
C	0016779	molecular_function	nucleotidyltransferase activity
C	0019363	biological_process	pyridine nucleotide biosynthetic process
C	0070566	molecular_function	adenylyltransferase activity
D	0000309	molecular_function	nicotinamide-nucleotide adenylyltransferase activity
D	0003824	molecular_function	catalytic activity
D	0004515	molecular_function	nicotinate-nucleotide adenylyltransferase activity
D	0005524	molecular_function	ATP binding
D	0009058	biological_process	biosynthetic process
D	0009165	biological_process	nucleotide biosynthetic process
D	0009435	biological_process	NAD biosynthetic process
D	0016779	molecular_function	nucleotidyltransferase activity
D	0019363	biological_process	pyridine nucleotide biosynthetic process
D	0070566	molecular_function	adenylyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE EPE A 301

Chain	Residue
A	TRP182
A	TYR183
A	ASP187
A	HOH402
A	HOH419
A	HOH430
C	SER67
C	ASN68
C	ARG70

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE DMS A 302

Chain	Residue
A	TYR58
A	SER72
A	VAL73

---

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE DMS B 301

Chain	Residue
B	TYR58
B	SER72
B	VAL73

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE DMS B 302

Chain	Residue
A	HOH423
B	ARG140
B	ASN141
B	GLU142
B	HIS143
B	ILE144

---

site_id	AC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EPE C 301

Chain	Residue
A	SER67
A	ASN68
A	PRO69
C	TRP182
C	TYR183
C	ASP187
C	HOH406
C	HOH445

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE DMS C 302

Chain	Residue
B	HOH403
C	TYR58
C	SER72
C	VAL73

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE DMS C 303

Chain	Residue
C	ARG140
C	ASN141
C	HIS143
C	ILE144
D	HOH417

---

site_id	AC8
Number of Residues	9
Details	BINDING SITE FOR RESIDUE EPE D 301

Chain	Residue
B	TRP182
B	TYR183
B	ASP187
D	SER67
D	ASN68
D	PRO69
D	ARG70
D	HOH405
D	HOH423

---

site_id	AC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EPE D 302

Chain	Residue
B	SER67
B	ASN68
B	ARG70
D	TRP182
D	TYR183
D	ASP187
D	HOH411

---

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE DMS D 303

Chain	Residue
D	SER72
D	VAL73

---

site_id	BC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE DMS D 304

Chain	Residue
D	TRP182
D	GLN191

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