4RMF

Biochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS, a promising TB drug target

Summary for 4RMF

Entry DOI	10.2210/pdb4rmf/pdb
Descriptor	Aspartate--tRNA(Asp/Asn) ligase, 2,2-bis(hydroxymethyl)propane-1,3-diol, FORMIC ACID, ... (4 entities in total)
Functional Keywords	alpha and beta proteins, trna synthetase, trna, ligase
Biological source	Mycobacterium smegmatis
Cellular location	Cytoplasm : A0QWN3
Total number of polymer chains	1
Total formula weight	66711.91
Authors	Cox, J.A.G.,Gurcha, S.S.,Veeraraghavan, U.,Besra, G.S.,Futterer, K. (deposition date: 2014-10-21, release date: 2014-11-19, Last modification date: 2023-09-20)
Primary citation	Gurcha, S.S.,Usha, V.,Cox, J.A.,Futterer, K.,Abrahams, K.A.,Bhatt, A.,Alderwick, L.J.,Reynolds, R.C.,Loman, N.J.,Nataraj, V.,Alemparte, C.,Barros, D.,Lloyd, A.J.,Ballell, L.,Hobrath, J.V.,Besra, G.S. Biochemical and Structural Characterization of Mycobacterial Aspartyl-tRNA Synthetase AspS, a Promising TB Drug Target. Plos One, 9:e113568-e113568, 2014 Cited by PubMed: 25409504 DOI: 10.1371/journal.pone.0113568 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation