4RMF
Biochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS, a promising TB drug target
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Aspartate--tRNA(Asp/Asn) ligase | polymer | 609 | 66529.7 | 1 | UniProt (A0QWN3) Pfam (PF01336) Pfam (PF00152) Pfam (PF02938) | Mycobacterium smegmatis | Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS |
| 2 | B (A) | 2,2-bis(hydroxymethyl)propane-1,3-diol | non-polymer | 136.1 | 1 | Chemie (3SY) | |||
| 3 | C (A) | FORMIC ACID | non-polymer | 46.0 | 1 | Chemie (FMT) | |||
| 4 | D (A) | water | water | 18.0 | 124 | Chemie (HOH) |
Sequence modifications
A: 1 - 598 (UniProt: A0QWN3)
| PDB | External Database | Details |
|---|---|---|
| Ala 599 | - | expression tag |
| Ala 600 | - | expression tag |
| Ala 601 | - | expression tag |
| Leu 602 | - | expression tag |
| Glu 603 | - | expression tag |
| His 604 | - | expression tag |
| His 605 | - | expression tag |
| His 606 | - | expression tag |
| His 607 | - | expression tag |
| His 608 | - | expression tag |
| His 609 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 66529.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 182.2 | |
| All* | Total formula weight | 66711.9 |
