4R9C

Crystal structure of Human galectin-3 CRD in complex with lactose (pH 7.5, PEG6000)

Summary for 4R9C

Related4R9A 4R9B 4R9D 4RL7
Related PRD IDPRD_900004
DescriptorGalectin-3, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose (3 entities in total)
Functional Keywordssugar binding protein
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm P17931
Total number of polymer chains1
Total molecular weight16584.95
Authors
Su, J.Y. (deposition date: 2014-09-04, release date: 2015-03-11, Last modification date: 2020-07-29)
Primary citation
Su, J.,Zhang, T.,Wang, P.,Liu, F.,Tai, G.,Zhou, Y.
The water network in galectin-3 ligand binding site guides inhibitor design
ACTA BIOCHIM.BIOPHYS.SIN., 2015
PubMed: 25662390 (PDB entries with the same primary citation)
DOI: 10.1093/abbs/gmu132
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.19 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.190500 2.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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PDB entries from 2020-09-23