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4R9C

Crystal structure of Human galectin-3 CRD in complex with lactose (pH 7.5, PEG6000)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Galectin-3polymer14416242.71UniProt (P17931)
Pfam (PF00337)
Homo sapiens (human)Gal-3, 35 kDa lectin, Carbohydrate-binding protein 35, CBP 35, Galactose-specific lectin 3, Galactoside-binding protein, GALBP, IgE-binding protein, L-31, Laminin-binding protein, Lectin L-29, Mac-2 antigen
2B
(B)
beta-D-galactopyranose-(1-4)-beta-D-glucopyranosebranched342.31In PDB
BIRD (PRD_900004)
GlyTouCan (G84224TW)
beta-lactose
3C
(A)
waterwater18.0300Chemie (HOH)
Sequence modifications
A: 111 - 250 (UniProt: P17931)
PDBExternal DatabaseDetails
Gly 107-expression tag
Ser 108-expression tag
His 109-expression tag
Met 110-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight16242.7
BranchedNumber of molecules1
Total formula weight342.3
All*Total formula weight16584.9
*Water molecules are not included.

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PDB entries from 2024-11-13

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