4R2G
Crystal Structure of PGT124 Fab bound to HIV-1 JRCSF gp120 core and to CD4
Summary for 4R2G
Entry DOI | 10.2210/pdb4r2g/pdb |
Related | 4R26 |
Descriptor | Surface protein gp160, T-cell surface glycoprotein CD4, PGT124 Light Chain, ... (9 entities in total) |
Functional Keywords | protein-protein complex, igg, anti-hiv antibodies, gp120, immune system |
Biological source | Human immunodeficiency virus type 1 group M subtype B (HIV-1) More |
Total number of polymer chains | 16 |
Total formula weight | 428760.14 |
Authors | Garces, F.,Wilson, I.A. (deposition date: 2014-08-11, release date: 2014-10-08, Last modification date: 2020-07-29) |
Primary citation | Garces, F.,Sok, D.,Kong, L.,McBride, R.,Kim, H.J.,Saye-Francisco, K.F.,Julien, J.P.,Hua, Y.,Cupo, A.,Moore, J.P.,Paulson, J.C.,Ward, A.B.,Burton, D.R.,Wilson, I.A. Structural Evolution of Glycan Recognition by a Family of Potent HIV Antibodies. Cell(Cambridge,Mass.), 159:69-79, 2014 Cited by PubMed: 25259921DOI: 10.1016/j.cell.2014.09.009 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.283 Å) |
Structure validation
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