4QTU

Structure of S. cerevisiae Bud23-Trm112 complex involved in formation of m7G1575 on 18S rRNA (SAM bound form)

Summary for 4QTU

Related4QTM 4QTT
DescriptorMultifunctional methyltransferase subunit TRM112, Putative methyltransferase BUD23, ZINC ION, ... (6 entities in total)
Functional Keywordsclass i, methyltransferase, transferase
Biological sourceSaccharomyces cerevisiae S288c (yeast)
Cellular locationCytoplasm  P53738 P25627
Total number of polymer chains4
Total molecular weight78359.51
Authors
Letoquart, J.,Huvelle, E.,Wacheul, L.,Bourgeois, G.,Zorbas, C.,Graille, M.,Heurgue-Hamard, V.,Lafontaine, D.L.J. (deposition date: 2014-07-09, release date: 2014-12-24, Last modification date: 2018-01-03)
Primary citation
Letoquart, J.,Huvelle, E.,Wacheul, L.,Bourgeois, G.,Zorbas, C.,Graille, M.,Heurgue-Hamard, V.,Lafontaine, D.L.J.
Structural and functional studies of Bud23-Trm112 reveal 18S rRNA N7-G1575 methylation occurs on late 40S precursor ribosomes
Proc.Natl.Acad.Sci.USA, 2014
PubMed: 25489090 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1413089111
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.124 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.229401.3%2.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution