4QTU
Structure of S. cerevisiae Bud23-Trm112 complex involved in formation of m7G1575 on 18S rRNA (SAM bound form)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000470 | biological_process | maturation of LSU-rRNA |
| A | 0002098 | biological_process | tRNA wobble uridine modification |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005730 | cellular_component | nucleolus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0005840 | cellular_component | ribosome |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0008276 | molecular_function | protein methyltransferase activity |
| A | 0016435 | molecular_function | rRNA (guanine) methyltransferase activity |
| A | 0018364 | biological_process | peptidyl-glutamine methylation |
| A | 0030488 | biological_process | tRNA methylation |
| A | 0030490 | biological_process | maturation of SSU-rRNA |
| A | 0035657 | cellular_component | eRF1 methyltransferase complex |
| A | 0042273 | biological_process | ribosomal large subunit biogenesis |
| A | 0042274 | biological_process | ribosomal small subunit biogenesis |
| A | 0043527 | cellular_component | tRNA methyltransferase complex |
| A | 0043528 | cellular_component | tRNA (m2G10) methyltransferase complex |
| A | 0046982 | molecular_function | protein heterodimerization activity |
| A | 0060566 | biological_process | positive regulation of termination of DNA-templated transcription |
| A | 0070476 | biological_process | rRNA (guanine-N7)-methylation |
| A | 0160102 | molecular_function | tRNA (guanine(10)-N2)-methyltransferase activity |
| B | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| B | 0016435 | molecular_function | rRNA (guanine) methyltransferase activity |
| B | 0070476 | biological_process | rRNA (guanine-N7)-methylation |
| C | 0000470 | biological_process | maturation of LSU-rRNA |
| C | 0002098 | biological_process | tRNA wobble uridine modification |
| C | 0005515 | molecular_function | protein binding |
| C | 0005634 | cellular_component | nucleus |
| C | 0005730 | cellular_component | nucleolus |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0005840 | cellular_component | ribosome |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0008276 | molecular_function | protein methyltransferase activity |
| C | 0016435 | molecular_function | rRNA (guanine) methyltransferase activity |
| C | 0018364 | biological_process | peptidyl-glutamine methylation |
| C | 0030488 | biological_process | tRNA methylation |
| C | 0030490 | biological_process | maturation of SSU-rRNA |
| C | 0035657 | cellular_component | eRF1 methyltransferase complex |
| C | 0042273 | biological_process | ribosomal large subunit biogenesis |
| C | 0042274 | biological_process | ribosomal small subunit biogenesis |
| C | 0043527 | cellular_component | tRNA methyltransferase complex |
| C | 0043528 | cellular_component | tRNA (m2G10) methyltransferase complex |
| C | 0046982 | molecular_function | protein heterodimerization activity |
| C | 0060566 | biological_process | positive regulation of termination of DNA-templated transcription |
| C | 0070476 | biological_process | rRNA (guanine-N7)-methylation |
| C | 0160102 | molecular_function | tRNA (guanine(10)-N2)-methyltransferase activity |
| D | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| D | 0016435 | molecular_function | rRNA (guanine) methyltransferase activity |
| D | 0070476 | biological_process | rRNA (guanine-N7)-methylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 201 |
| Chain | Residue |
| A | CYS11 |
| A | CYS16 |
| A | CYS112 |
| A | CYS115 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 202 |
| Chain | Residue |
| A | LYS14 |
| A | LEU134 |
| A | HOH309 |
| B | ARG139 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE EDO A 203 |
| Chain | Residue |
| A | GLN36 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 204 |
| Chain | Residue |
| A | HIS117 |
| A | ILE118 |
| A | TYR119 |
| A | TYR120 |
| A | ASN127 |
| A | LEU129 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 205 |
| Chain | Residue |
| A | LEU48 |
| A | ASP52 |
| A | PHE78 |
| A | PRO79 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 206 |
| Chain | Residue |
| A | ASP87 |
| B | TYR159 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 207 |
| Chain | Residue |
| A | HOH315 |
| A | HOH317 |
| A | HOH338 |
| B | GLN121 |
| B | TRP122 |
| B | LYS161 |
| site_id | AC8 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE SAM B 301 |
| Chain | Residue |
| B | TYR22 |
| B | GLN32 |
| B | GLY55 |
| B | CYS56 |
| B | GLY57 |
| B | LEU60 |
| B | SER61 |
| B | ASP77 |
| B | ILE78 |
| B | SER79 |
| B | MET82 |
| B | GLN98 |
| B | ASP99 |
| B | MET100 |
| B | ILE117 |
| B | SER118 |
| B | ALA119 |
| B | TRP122 |
| B | EDO302 |
| B | HOH401 |
| B | HOH406 |
| B | HOH438 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 302 |
| Chain | Residue |
| A | THR86 |
| A | ASP87 |
| A | ASP88 |
| B | SAM301 |
| site_id | BC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO B 303 |
| Chain | Residue |
| B | ARG139 |
| B | ASN142 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 304 |
| Chain | Residue |
| B | LEU170 |
| B | LYS174 |
| B | PHE178 |
| B | SER179 |
| B | GLY180 |
| D | ASP186 |
| D | GLU188 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 305 |
| Chain | Residue |
| B | GLU188 |
| D | LEU170 |
| D | GLY180 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 306 |
| Chain | Residue |
| B | SER25 |
| B | THR26 |
| B | ARG27 |
| site_id | BC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO B 307 |
| Chain | Residue |
| B | GLN67 |
| B | GLU68 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 308 |
| Chain | Residue |
| A | ASN43 |
| B | ASP70 |
| B | HIS71 |
| B | VAL72 |
| B | GLU92 |
| B | HOH422 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 309 |
| Chain | Residue |
| B | LEU45 |
| B | GLU68 |
| B | HIS71 |
| B | HOH408 |
| site_id | BC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 310 |
| Chain | Residue |
| B | ILE12 |
| B | TYR14 |
| B | SER79 |
| B | PRO80 |
| B | SER81 |
| B | HOH458 |
| site_id | BC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 311 |
| Chain | Residue |
| B | ARG38 |
| D | VAL198 |
| D | EDO302 |
| site_id | CC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 201 |
| Chain | Residue |
| C | CYS11 |
| C | CYS16 |
| C | CYS112 |
| C | CYS115 |
| site_id | CC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO C 202 |
| Chain | Residue |
| C | SER77 |
| A | THR18 |
| A | SER19 |
| A | ASN20 |
| A | ASP21 |
| A | HOH332 |
| C | LYS75 |
| site_id | CC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO C 203 |
| Chain | Residue |
| C | ILE118 |
| C | TYR119 |
| C | TYR120 |
| C | ASN127 |
| site_id | CC4 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE SAM D 301 |
| Chain | Residue |
| D | TYR22 |
| D | GLN32 |
| D | GLY55 |
| D | CYS56 |
| D | GLY57 |
| D | LEU60 |
| D | SER61 |
| D | ASP77 |
| D | ILE78 |
| D | SER79 |
| D | MET82 |
| D | GLN98 |
| D | ASP99 |
| D | MET100 |
| D | ILE117 |
| D | SER118 |
| D | TRP122 |
| D | HOH401 |
| site_id | CC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO D 302 |
| Chain | Residue |
| B | VAL183 |
| B | VAL198 |
| B | EDO311 |
| D | ARG38 |
