4QTT

Structure of S. cerevisiae Bud23-Trm112 complex involved in formation of m7G1575 on 18S rRNA (apo-form)

Summary for 4QTT

Entry DOI	10.2210/pdb4qtt/pdb
Related	4QTM 4QTU
Descriptor	Multifunctional methyltransferase subunit TRM112, Putative methyltransferase BUD23, ZINC ION, ... (6 entities in total)
Functional Keywords	class i mtase, methyltransferase, methylation, transferase
Biological source	Saccharomyces cerevisiae S288c (yeast) More
Cellular location	Cytoplasm : P53738 P25627
Total number of polymer chains	4
Total formula weight	77178.26
Authors	Letoquart, J.,Huvelle, E.,Wacheul, L.,Bourgeois, G.,Zorbas, C.,Graille, M.,Heurgue-Hamard, V.,Lafontaine, D.L.J. (deposition date: 2014-07-09, release date: 2014-12-24, Last modification date: 2022-08-24)
Primary citation	Letoquart, J.,Huvelle, E.,Wacheul, L.,Bourgeois, G.,Zorbas, C.,Graille, M.,Heurgue-Hamard, V.,Lafontaine, D.L. Structural and functional studies of Bud23-Trm112 reveal 18S rRNA N7-G1575 methylation occurs on late 40S precursor ribosomes. Proc.Natl.Acad.Sci.USA, 111:E5518-E5526, 2014 Cited by PubMed: 25489090 DOI: 10.1073/pnas.1413089111 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation