4QGZ

X-ray structure of the adduct formed between hen egg white lysozyme and trans-dimethylamine methylamine dichlorido platinum(II)

Summary for 4QGZ

Entry DOI	10.2210/pdb4qgz/pdb
Related	2I6Z 4J1A 4J1B 4LFK 4LFP 4LGK 4MR1 4NY5 4QH3
Descriptor	Lysozyme C, bis(chloranyl)-(dimethylamino)-(methylamino)platinum (3 entities in total)
Functional Keywords	lysozyme fold, hydrolase, o-glycosyl hydrolase
Biological source	Gallus gallus (bantam,chickens)
Cellular location	Secreted: P00698
Total number of polymer chains	1
Total formula weight	15011.38
Authors	Russo Krauss, I.,Merlino, A. (deposition date: 2014-05-26, release date: 2014-07-30, Last modification date: 2014-08-20)
Primary citation	Messori, L.,Marzo, T.,Michelucci, E.,Russo Krauss, I.,Navarro-Ranninger, C.,Quiroga, A.G.,Merlino, A. Interactions between Anticancer trans-Platinum Compounds and Proteins: Crystal Structures and ESI-MS Spectra of Two Protein Adducts of trans-(Dimethylamino)(methylamino)dichloridoplatinum(II). Inorg.Chem., 53:7806-7808, 2014 Cited by PubMed: 25025479 DOI: 10.1021/ic5012583 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.51 Å)

Structure validation