4QH3
X-ray structure of the adduct formed between bovine pancreatic ribonuclease and trans-dimethylamine methylamine dichlorido platinum(II)
Summary for 4QH3
Entry DOI | 10.2210/pdb4qh3/pdb |
Related | 4QGZ |
Descriptor | Ribonuclease pancreatic, bis(chloranyl)-(dimethylamino)-(methylamino)platinum (3 entities in total) |
Functional Keywords | hydrolase, rna binding |
Biological source | Bos taurus (bovine,cow,domestic cattle,domestic cow) |
Cellular location | Secreted: P61823 |
Total number of polymer chains | 2 |
Total formula weight | 30137.52 |
Authors | Russo Krauss, I.,Merlino, A. (deposition date: 2014-05-26, release date: 2014-07-30, Last modification date: 2014-08-20) |
Primary citation | Messori, L.,Marzo, T.,Michelucci, E.,Russo Krauss, I.,Navarro-Ranninger, C.,Quiroga, A.G.,Merlino, A. Interactions between Anticancer trans-Platinum Compounds and Proteins: Crystal Structures and ESI-MS Spectra of Two Protein Adducts of trans-(Dimethylamino)(methylamino)dichloridoplatinum(II). Inorg.Chem., 53:7806-7808, 2014 Cited by PubMed: 25025479DOI: 10.1021/ic5012583 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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