4Q9U
Crystal structure of the Rab5, Rabex-5delta and Rabaptin-5C21 complex
Summary for 4Q9U
Entry DOI | 10.2210/pdb4q9u/pdb |
Related | 4N3X 4N3Y 4N3Z |
Descriptor | Rab5 GDP/GTP exchange factor, Ras-related protein Rab-5A, Rab GTPase-binding effector protein 1 (3 entities in total) |
Functional Keywords | rab5, rabex-5, rabaptin-5, gef activity, endocytosis, early endosomes, vps9, coiled-coil, gef, effector, small gtpases |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm : Q9UJ41 Q15276 Cell membrane ; Lipid-anchor ; Cytoplasmic side : P20339 |
Total number of polymer chains | 8 |
Total formula weight | 155595.35 |
Authors | |
Primary citation | Zhang, Z.,Zhang, T.,Wang, S.,Gong, Z.,Tang, C.,Chen, J.,Ding, J. Molecular mechanism for Rabex-5 GEF activation by Rabaptin-5 Elife, 3:e02687-e02687, 2014 Cited by PubMed: 24957337DOI: 10.7554/eLife.02687 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4.618 Å) |
Structure validation
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