4Q8V
tRNA-Guanine Transglycosylase (TGT) in Complex with 4-[2-({6-Amino-8-oxo-1H,7H,8H-imidazo[4,5-g]quinazolin-2-yl}amino)ethyl]benzonitrile
Summary for 4Q8V
Entry DOI | 10.2210/pdb4q8v/pdb |
Related | 1P0D 4Q8T 4Q8U 4Q8W |
Descriptor | Queuine tRNA-ribosyltransferase, ZINC ION, GLYCEROL, ... (5 entities in total) |
Functional Keywords | guanine exchange enzyme, preq1, trna, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Zymomonas mobilis subsp. mobilis |
Total number of polymer chains | 1 |
Total formula weight | 43572.69 |
Authors | |
Primary citation | Neeb, M.,Hohn, C.,Heine, A.,Diederich, F.,Klebe, G. Addressing a New Subpocket of TGT by Elongated 2-Amino-lin-benzoguanines To be Published, |
Experimental method | X-RAY DIFFRACTION (1.396 Å) |
Structure validation
Download full validation report