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4Q8V

tRNA-Guanine Transglycosylase (TGT) in Complex with 4-[2-({6-Amino-8-oxo-1H,7H,8H-imidazo[4,5-g]quinazolin-2-yl}amino)ethyl]benzonitrile

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Queuine tRNA-ribosyltransferasepolymer38843069.81UniProt (P28720)
Pfam (PF01702)
Zymomonas mobilis subsp. mobilisGuanine insertion enzyme, tRNA-guanine transglycosylase
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
4D
(A)
4-{2-[(6-amino-8-oxo-7,8-dihydro-1H-imidazo[4,5-g]quinazolin-2-yl)amino]ethyl}benzonitrilenon-polymer345.41Chemie (2YX)
5E
(A)
waterwater18.0385Chemie (HOH)
Sequence modifications
A: 1 - 386 (UniProt: P28720)
PDBExternal DatabaseDetails
Gly -1-expression tag
Ser 0-expression tag
Lys 312Thr 312SEE REMARK 999
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight43069.8
Non-Polymers*Number of molecules3
Total formula weight502.9
All*Total formula weight43572.7
*Water molecules are not included.

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PDB entries from 2025-12-03

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