4Q2G

CRYSTAL STRUCTURE OF AN INTRAMEMBRANE CDP-DAG SYNTHETASE CENTRAL FOR PHOSPHOLIPID BIOSYNTHESIS (S200C/S223C, inactive mutant)

4Q2G の概要

• エントリーDOI: 10.2210/pdb4q2g/pdb
• 関連するPDBエントリー: 4Q2E
• 分子名称: Phosphatidate cytidylyltransferase, MERCURY (II) ION, MAGNESIUM ION, ... (4 entities in total)
• 機能のキーワード: intramembrane enzyme, cdsa fold, phospholipid biosynthesis lipid metabolism, ctp and phosphatidic acid binding, nucleotidyltransferase, membrane, transferase
• 由来する生物種: Thermotoga maritima MSB8
• 細胞内の位置: Cell membrane; Multi-pass membrane protein (By similarity): Q9X1B7
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 66117.56

構造登録者

Liu, X.,Yin, Y.,Wu, J.,Liu, Z. (登録日: 2014-04-08, 公開日: 2014-07-02, 最終更新日: 2024-03-20)

• 主引用文献: Liu, X.,Yin, Y.,Wu, J.,Liu, Z.; Structure and mechanism of an intramembrane liponucleotide synthetase central for phospholipid biosynthesis; Nat Commun, 5:4244-4244, 2014; PubMed: 24968740; DOI: 10.1038/ncomms5244

実験手法

X-RAY DIFFRACTION (3.4 Å)