4PSG
Crystal Structure of C.elegans Thymidylate Synthase in complex with an inhibitor N(4)OHdCMP
Summary for 4PSG
Entry DOI | 10.2210/pdb4psg/pdb |
Related | 4ein 4ez8 4g9u 4iqb 4iqq 4irr |
Descriptor | Thymidylate synthase, 2'-deoxy-N-hydroxycytidine 5'-(dihydrogen phosphate) (3 entities in total) |
Functional Keywords | enzyme, methyltransferase, nucleotide biosynthesis, protein dimer, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Caenorhabditis elegans (roundworm) |
Total number of polymer chains | 2 |
Total formula weight | 72358.20 |
Authors | Wilk, P.,Jarmula, A.,Rode, W. (deposition date: 2014-03-07, release date: 2015-02-18, Last modification date: 2024-02-28) |
Primary citation | Dowiercia, A.,Wilk, P.,Rypniewski, W.,Rode, W.,Jarmua, A. Crystal Structure of C.elegans Thymidylate Synthase in complex with an inhibitor N(4)OHdCMP To be Published, |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
Download full validation report