4PSG

Crystal Structure of C.elegans Thymidylate Synthase in complex with an inhibitor N(4)OHdCMP

4PSG の概要

• エントリーDOI: 10.2210/pdb4psg/pdb
• 関連するPDBエントリー: 4ein 4ez8 4g9u 4iqb 4iqq 4irr
• 分子名称: Thymidylate synthase, 2'-deoxy-N-hydroxycytidine 5'-(dihydrogen phosphate) (3 entities in total)
• 機能のキーワード: enzyme, methyltransferase, nucleotide biosynthesis, protein dimer, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Caenorhabditis elegans (roundworm)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 72358.20

構造登録者

Wilk, P.,Jarmula, A.,Rode, W. (登録日: 2014-03-07, 公開日: 2015-02-18, 最終更新日: 2024-02-28)

• 主引用文献: Dowiercia, A.,Wilk, P.,Rypniewski, W.,Rode, W.,Jarmua, A.; Crystal Structure of C.elegans Thymidylate Synthase in complex with an inhibitor N(4)OHdCMP; To be Published,

実験手法

X-RAY DIFFRACTION (2.8 Å)