4PAO

A conserved phenylalanine as relay between the 5 helix and the GDP binding region of heterotrimeric G protein

4PAO の概要

• エントリーDOI: 10.2210/pdb4pao/pdb
• 関連するPDBエントリー: 4PAM 4PAN 4PAQ
• 分子名称: Guanine nucleotide-binding protein G(i) subunit alpha-1, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
• 機能のキーワード: activation of heterotrimeric g protein gdp release, computer modeling, g protein coupled receptors, rhodopsin, signaling protein
• 由来する生物種: Rattus norvegicus (Rat)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 40918.55

構造登録者

Kaya, A.I.,Lokits, A.D.,Gilbert, J.,Iverson, T.M.,Meiler, J.,Hamm, H.E. (登録日: 2014-04-09, 公開日: 2014-07-30, 最終更新日: 2023-09-27)

• 主引用文献: Kaya, A.I.,Lokits, A.D.,Gilbert, J.A.,Iverson, T.M.,Meiler, J.,Hamm, H.E.; A Conserved Phenylalanine as a Relay between the alpha 5 Helix and the GDP Binding Region of Heterotrimeric Gi Protein alpha Subunit.; J.Biol.Chem., 289:24475-24487, 2014; PubMed: 25037222; DOI: 10.1074/jbc.M114.572875

実験手法

X-RAY DIFFRACTION (2.003 Å)