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4PAO

A conserved phenylalanine as relay between the 5 helix and the GDP binding region of heterotrimeric G protein

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Guanine nucleotide-binding protein G(i) subunit alpha-1polymer35440355.01UniProt (P10824)
Pfam (PF00503)
Rattus norvegicus (Rat)Adenylate cyclase-inhibiting G alpha protein
2B
(A)
5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATEnon-polymer539.21Chemie (GSP)
3C
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
4D
(A)
waterwater18.0182Chemie (HOH)
Sequence modifications
A: 1 - 354 (UniProt: P10824)
PDBExternal DatabaseDetails
Cys 336Phe 336engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight40355.0
Non-Polymers*Number of molecules2
Total formula weight563.6
All*Total formula weight40918.6
*Water molecules are not included.

246905

PDB entries from 2025-12-31

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