4P6W
Crystal Structure of mometasone furoate-bound glucocorticoid receptor ligand binding domain
Summary for 4P6W
Entry DOI | 10.2210/pdb4p6w/pdb |
Related | 4P6X |
Descriptor | Glucocorticoid receptor, Nuclear receptor coactivator 2, MOMETASONE FUROATE, ... (4 entities in total) |
Functional Keywords | mometasone furoate, glucocorticoid receptor, potency, hormone-hormone receptor complex, hormone receptor-hormone activator complex, hormone receptor/hormone activator |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 31212.09 |
Authors | He, Y.,Zhou, X.E.,Tolbert, W.D.,Powell, K.,Melcher, K.,Xu, H.E. (deposition date: 2014-03-25, release date: 2014-04-16, Last modification date: 2023-12-27) |
Primary citation | He, Y.,Yi, W.,Suino-Powell, K.,Zhou, X.E.,Tolbert, W.D.,Tang, X.,Yang, J.,Yang, H.,Shi, J.,Hou, L.,Jiang, H.,Melcher, K.,Xu, H.E. Structures and mechanism for the design of highly potent glucocorticoids. Cell Res., 24:713-726, 2014 Cited by PubMed: 24763108DOI: 10.1038/cr.2014.52 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.951 Å) |
Structure validation
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