4P6W
Crystal Structure of mometasone furoate-bound glucocorticoid receptor ligand binding domain
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | binding site for residue MOF A 801 |
| Chain | Residue |
| A | MET560 |
| A | PHE623 |
| A | MET639 |
| A | GLN642 |
| A | MET646 |
| A | TYR735 |
| A | CYS736 |
| A | THR739 |
| A | PHE749 |
| A | LEU563 |
| A | ASN564 |
| A | GLY567 |
| A | GLN570 |
| A | TRP600 |
| A | MET601 |
| A | MET604 |
| A | ARG611 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 165 |
| Details | Region: {"description":"Interaction with CRY1","evidences":[{"source":"PubMed","id":"22170608","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)","evidences":[{"source":"PubMed","id":"12144530","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Motif: {"description":"LXXLL motif 3"} |
| Chain | Residue | Details |
