4OGW

Structure of a human CD38 mutant complexed with NMN

Summary for 4OGW

Entry DOI	10.2210/pdb4ogw/pdb
Descriptor	ADP-ribosyl cyclase 1, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE (3 entities in total)
Functional Keywords	adp-ribosyl cyclase, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Membrane; Single-pass type II membrane protein: P28907
Total number of polymer chains	1
Total formula weight	29997.84
Authors	Shewchuk, L.M.,Preugschat, F.,Carter, L.H.,Boros, E.E.,Moyer, M.B.,Stewart, E.L.,Porter, D.J.T. (deposition date: 2014-01-16, release date: 2014-10-08, Last modification date: 2023-09-20)
Primary citation	Preugschat, F.,Carter, L.H.,Boros, E.E.,Porter, D.J.,Stewart, E.L.,Shewchuk, L.M. A pre-steady state and steady state kinetic analysis of the N-ribosyl hydrolase activity of hCD157. Arch.Biochem.Biophys., 564C:156-163, 2014 Cited by PubMed: 25250980 DOI: 10.1016/j.abb.2014.09.008 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation