4OGW
Structure of a human CD38 mutant complexed with NMN
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ADP-ribosyl cyclase 1 | polymer | 257 | 29662.6 | 1 | UniProt (P28907) Pfam (PF02267) | Homo sapiens (human) | Cyclic ADP-ribose hydrolase 1, cADPr hydrolase 1, T10 |
| 2 | B (A) | BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE | non-polymer | 335.2 | 1 | Chemie (NMN) PubChem (939) PubChem (177675032) PubChem (44269211) PubChem (46874984) PubChem (71750998) PubChem (14181) PubChem (89516131) PubChem (9819044) PubChem (93605785) PubChem (90476335) PubChem (6093202) PubChem (122587981) PubChem (123929622) PubChem (124350426) PubChem (15737496) PubChem (134694109) PubChem (147327152) PubChem (149999359) PubChem (164745794) PubChem (167012155) PubChem (172887170) | |||
| 3 | C (A) | water | water | 18.0 | 189 | Chemie (HOH) |
Sequence modifications
A: 46 - 300 (UniProt: P28907)
| PDB | External Database | Details |
|---|---|---|
| Gly 44 | - | expression tag |
| Ser 45 | - | expression tag |
| Asp 100 | Asn 100 | engineered mutation |
| Ala 164 | Asn 164 | engineered mutation |
| Asp 209 | Asn 209 | engineered mutation |
| Asp 219 | Asn 219 | engineered mutation |
| Gln 226 | Glu 226 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29662.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 335.2 | |
| All* | Total formula weight | 29997.8 |
