4OGW
Structure of a human CD38 mutant complexed with NMN
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ADP-ribosyl cyclase 1 | polymer | 257 | 29662.6 | 1 | UniProt (P28907) Pfam (PF02267) | Homo sapiens (human) | Cyclic ADP-ribose hydrolase 1, cADPr hydrolase 1, T10 |
| 2 | B (A) | BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE | non-polymer | 335.2 | 1 | Chemie (NMN) | |||
| 3 | C (A) | water | water | 18.0 | 189 | Chemie (HOH) |
Sequence modifications
A: 46 - 300 (UniProt: P28907)
| PDB | External Database | Details |
|---|---|---|
| Gly 44 | - | expression tag |
| Ser 45 | - | expression tag |
| Asp 100 | Asn 100 | engineered mutation |
| Ala 164 | Asn 164 | engineered mutation |
| Asp 209 | Asn 209 | engineered mutation |
| Asp 219 | Asn 219 | engineered mutation |
| Gln 226 | Glu 226 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29662.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 335.2 | |
| All* | Total formula weight | 29997.8 |
