4O43
DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities
Summary for 4O43
Entry DOI | 10.2210/pdb4o43/pdb |
Related | 4NZV 4O24 4O4K 4O5G |
Descriptor | Exonuclease, putative, MANGANESE (II) ION, (5~{E})-3-[(2~{R})-butan-2-yl]-5-[(4-hydroxyphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one, ... (4 entities in total) |
Functional Keywords | dna repair dna double-strand break repair thermophilic mre11 nuclease, dna repair dna double-strand break repair, dna binding protein-inhibitor complex, dna binding protein/inhibitor |
Biological source | Thermotoga maritima |
Total number of polymer chains | 2 |
Total formula weight | 77956.99 |
Authors | Shibata, A.,Moiani, D.,Arvai, A.S.,Perry, J.,Harding, S.M.,Genois, M.,Maity, R.,Rossum-Fikkert, S.,Kertokalio, A.,Romoli, F.,Ismail, A.,Ismalaj, E.,Petricci, E.,Neale, M.J.,Bristow, R.G.,Masson, J.,Wyman, C.,Jeggo, P.A.,Tainer, J.A. (deposition date: 2013-12-18, release date: 2014-01-08, Last modification date: 2023-09-20) |
Primary citation | Shibata, A.,Moiani, D.,Arvai, A.S.,Perry, J.,Harding, S.M.,Genois, M.M.,Maity, R.,van Rossum-Fikkert, S.,Kertokalio, A.,Romoli, F.,Ismail, A.,Ismalaj, E.,Petricci, E.,Neale, M.J.,Bristow, R.G.,Masson, J.Y.,Wyman, C.,Jeggo, P.A.,Tainer, J.A. DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities. Mol.Cell, 53:7-18, 2014 Cited by PubMed: 24316220DOI: 10.1016/j.molcel.2013.11.003 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
Download full validation report