4NYV

Crystal Structure of the Bromodomain of human CREBBP in complex with a quinazolin-one ligand

4NYV の概要

• エントリーDOI: 10.2210/pdb4nyv/pdb
• 関連するPDBエントリー: 4NYW 4NYX
• 分子名称: CREB-binding protein, 6-bromo-3-methyl-3,4-dihydroquinazolin-2(1H)-one (3 entities in total)
• 機能のキーワード: crebbp, creb binding, kat3a, rsts, rst, bromodomain, transcription, structural genomics consortium, sgc
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: Q92793
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 57857.74

構造登録者

Filippakopoulos, P.,Picaud, S.,Felletar, I.,Fedorov, O.,Martin, S.,Monteiro, O.P.,von Delft, F.,Brennan, P.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2013-12-11, 公開日: 2014-01-29, 最終更新日: 2023-09-20)

• 主引用文献: Filippakopoulos, P.,Picaud, S.,Felletar, I.,Fedorov, O.,Martin, S.,Monteiro, O.P.,von Delft, F.,Brennan, P.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.; Crystal Structure of the Bromodomain of human CREBBP in complex with a quinazolin-one ligand; TO BE PUBLISHED,

実験手法

X-RAY DIFFRACTION (1.83 Å)