4NYV
Crystal Structure of the Bromodomain of human CREBBP in complex with a quinazolin-one ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | CREB-binding protein | polymer | 119 | 14223.3 | 4 | UniProt (Q92793) Pfam (PF00439) | Homo sapiens (human) | |
| 2 | E, F, G, H (A, B, C, D) | 6-bromo-3-methyl-3,4-dihydroquinazolin-2(1H)-one | non-polymer | 241.1 | 4 | Chemie (15E) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 262 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1081 - 1197 (UniProt: Q92793)
| PDB | External Database | Details |
|---|---|---|
| Ser 1079 | - | expression tag |
| Met 1080 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 56893.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 964.3 | |
| All* | Total formula weight | 57857.7 |
