4NXP
Crystal Structure of Free T-cell Lymphoma Invasion and Metastasis-1 PDZ Domain Quadruple Mutant (QM)
Summary for 4NXP
Entry DOI | 10.2210/pdb4nxp/pdb |
Related | 3KZD 3KZE 4GVC 4GVD 4NXQ 4NXR |
Descriptor | T-lymphoma invasion and metastasis-inducing protein 1 (2 entities in total) |
Functional Keywords | beta barrel fold protein, pdz domain, peptide binding, specificity mutant, scaffold signaling protein for cell adhesion and cell junction, signaling domain, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Cell junction: Q13009 |
Total number of polymer chains | 1 |
Total formula weight | 10192.40 |
Authors | Liu, X.,Speckhard, D.C.,Shepherd, T.R.,Hengel, S.R.,Fuentes, E.J. (deposition date: 2013-12-09, release date: 2015-05-13, Last modification date: 2023-09-20) |
Primary citation | Liu, X.,Speckhard, D.C.,Shepherd, T.R.,Sun, Y.J.,Hengel, S.R.,Yu, L.,Fowler, C.A.,Gakhar, L.,Fuentes, E.J. Distinct Roles for Conformational Dynamics in Protein-Ligand Interactions. Structure, 24:2053-2066, 2016 Cited by PubMed: 27998539DOI: 10.1016/j.str.2016.08.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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