4NND

Structural basis of PTPN18 fingerprint on distinct HER2 tyrosine phosphorylation sites

Summary for 4NND

• Entry DOI: 10.2210/pdb4nnd/pdb
• Descriptor: Tyrosine-protein phosphatase non-receptor type 18, Receptor tyrosine-protein kinase erbB-2 (3 entities in total)
• Functional Keywords: beta barrel, beta-propeller, kinase binding, phosphorylation, hydrolase
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus : Q99952; Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Cytoplasm. Isoform 3: Cytoplasm: P04626
• Total number of polymer chains: 8
• Total formula weight: 135814.81

Authors

Wang, H.,Yang, F.,Yang, D.,Du, Y. (deposition date: 2013-11-17, release date: 2014-11-19)

• Primary citation: Wang, H.,Yang, F.,Yang, D.,Du, Y.; Structural basis of PTPN18 fingerprint on distinct HER2 tyrosine phosphorylation sites; To be Published,

Experimental method

X-RAY DIFFRACTION (2.502 Å)