4NND
Structural basis of PTPN18 fingerprint on distinct HER2 tyrosine phosphorylation sites
Summary for 4NND
Entry DOI | 10.2210/pdb4nnd/pdb |
Descriptor | Tyrosine-protein phosphatase non-receptor type 18, Receptor tyrosine-protein kinase erbB-2 (3 entities in total) |
Functional Keywords | beta barrel, beta-propeller, kinase binding, phosphorylation, hydrolase |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus : Q99952 Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Cytoplasm. Isoform 3: Cytoplasm: P04626 |
Total number of polymer chains | 8 |
Total formula weight | 135814.81 |
Authors | |
Primary citation | Wang, H.,Yang, F.,Yang, D.,Du, Y. Structural basis of PTPN18 fingerprint on distinct HER2 tyrosine phosphorylation sites To be Published, |
Experimental method | X-RAY DIFFRACTION (2.502 Å) |
Structure validation
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