4NIF

Heterodimeric structure of ERK2 and RSK1

Summary for 4NIF

Entry DOI	10.2210/pdb4nif/pdb
Descriptor	Ribosomal protein S6 kinase alpha-1, Mitogen-activated protein kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (6 entities in total)
Functional Keywords	kinase domain, signaling, substrate kinase binding, transferase
Biological source	Homo sapiens (human) More
Cellular location	Nucleus: Q15418 Cytoplasm, cytoskeleton, spindle : P28482
Total number of polymer chains	4
Total formula weight	159509.75
Authors	Gogl, G.,Remenyi, A. (deposition date: 2013-11-06, release date: 2014-11-12, Last modification date: 2023-11-08)
Primary citation	Alexa, A.,Gogl, G.,Glatz, G.,Garai, A.,Zeke, A.,Varga, J.,Dudas, E.,Jeszenoi, N.,Bodor, A.,Hetenyi, C.,Remenyi, A. Structural assembly of the signaling competent ERK2-RSK1 heterodimeric protein kinase complex Proc.Natl.Acad.Sci.USA, 112:2711-2716, 2015 Cited by PubMed: 25730857 DOI: 10.1073/pnas.1417571112 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation