4NCL

Crystal structure of eukaryotic translation initiation factor eIF5B (517-970) from Chaetomium thermophilum in complex with GDP

Summary for 4NCL

• Entry DOI: 10.2210/pdb4ncl/pdb
• Related: 4NCF 4NCN
• Descriptor: Eukaryotic translation initiation factor 5B-like protein, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: translation initiation, gtpase, eif5b/if2, subunit joining, ribosome, translation
• Biological source: Chaetomium thermophilum var. thermophilum
• Cellular location: Cytoplasm : G0S8G9
• Total number of polymer chains: 2
• Total formula weight: 102880.04

Authors

Kuhle, B.,Ficner, R. (deposition date: 2013-10-24, release date: 2014-07-09, Last modification date: 2023-09-20)

• Primary citation: Kuhle, B.,Ficner, R.; eIF5B employs a novel domain release mechanism to catalyze ribosomal subunit joining.; Embo J., 33:1177-1191, 2014; PubMed: 24686316; DOI: 10.1002/embj.201387344

Experimental method

X-RAY DIFFRACTION (2.115 Å)