4NCL
Crystal structure of eukaryotic translation initiation factor eIF5B (517-970) from Chaetomium thermophilum in complex with GDP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Eukaryotic translation initiation factor 5B-like protein | polymer | 457 | 50972.5 | 2 | UniProt (G0S8G9) Pfam (PF00009) Pfam (PF11987) | Chaetomium thermophilum var. thermophilum | |
| 2 | C, E (A, B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 3 | D, F (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 192 | Chemie (HOH) |
Sequence modifications
A, B: 517 - 970 (UniProt: G0S8G9)
| PDB | External Database | Details |
|---|---|---|
| Ser 514 | - | expression tag |
| His 515 | - | expression tag |
| Met 516 | - | expression tag |
| Val 576 | - | SEE REMARK 999 |
| Val 577 | - | SEE REMARK 999 |
| Asn 578 | - | SEE REMARK 999 |
| Lys 579 | - | SEE REMARK 999 |
| Asp 580 | - | SEE REMARK 999 |
| Gly 581 | - | SEE REMARK 999 |
| Lys 582 | - | SEE REMARK 999 |
| Phe 583 | - | SEE REMARK 999 |
| Glu 584 | - | SEE REMARK 999 |
| Phe 585 | - | SEE REMARK 999 |
| Lys 586 | - | SEE REMARK 999 |
| Val 587 | - | SEE REMARK 999 |
| Pro 588 | - | SEE REMARK 999 |
| Gly 589 | - | SEE REMARK 999 |
| Leu 590 | - | SEE REMARK 999 |
| Leu 591 | - | SEE REMARK 999 |
| Ile 592 | - | SEE REMARK 999 |
| Ile 593 | - | SEE REMARK 999 |
| Asp 594 | - | SEE REMARK 999 |
| Thr 595 | - | SEE REMARK 999 |
| Pro 596 | - | SEE REMARK 999 |
| Gly 597 | - | SEE REMARK 999 |
| His 598 | - | SEE REMARK 999 |
| Glu 599 | - | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 101945.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 935.0 | |
| All* | Total formula weight | 102880.0 |
