4NCB
Structure of Thermus thermophilus Argonaute bound to guide DNA and 19-mer target DNA with Mg2+
Summary for 4NCB
Entry DOI | 10.2210/pdb4ncb/pdb |
Related | 4N41 4N47 4N76 4NCA |
Descriptor | Argonaute, 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3', 5'-D(*TP*AP*TP*AP*CP*AP*AP*CP*C)-3', ... (8 entities in total) |
Functional Keywords | argonaute, rna interference, dna interference, piwi, nuclear protein-dna complex, nuclear protein/dna |
Biological source | Thermus thermophilus |
Total number of polymer chains | 8 |
Total formula weight | 181480.54 |
Authors | |
Primary citation | Sheng, G.,Zhao, H.,Wang, J.,Rao, Y.,Tian, W.,Swarts, D.C.,van der Oost, J.,Patel, D.J.,Wang, Y. Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage. Proc.Natl.Acad.Sci.USA, 111:652-657, 2014 Cited by PubMed: 24374628DOI: 10.1073/pnas.1321032111 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.189 Å) |
Structure validation
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