4NCB

Structure of Thermus thermophilus Argonaute bound to guide DNA and 19-mer target DNA with Mg2+

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Argonaute	polymer	685	76728.7	2	UniProt (Q746M7) Pfam (PF22472) Pfam (PF18309) Pfam (PF22474)	Thermus thermophilus
2	C, F (C, E)	5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3'	polymer	21	6588.3	2
3	D, H (P, H)	5'-D(*TP*AP*TP*AP*CP*AP*AP*CP*C)-3'	polymer	9	2683.8	2
4	E (D)	5'-D(*TP*AP*TP*AP*CP*AP*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3'	polymer	19	5708.7	1
5	G (F)	5'-D(P*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3'	polymer	10	2980.0	1
6	I, K (A, B)	THYMIDINE-5'-PHOSPHATE	non-polymer		322.2	2	Chemie (TMP)
7	J, L, M, N, O... (A, B, C, D, E)	MAGNESIUM ION	non-polymer		24.3	6	Chemie (MG)
8	Q, R, S, T, U... (A, B, C, P, D...)	water	water		18.0	444	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	180690.3
Non-Polymers*	Number of molecules	8
	Total formula weight	790.2
All*	Total formula weight	181480.5

*Water molecules are not included.