4N9J
Crystal structure of the cryptic polo box domain of human Plk4
Summary for 4N9J
Entry DOI | 10.2210/pdb4n9j/pdb |
Related | 4N7V 4N7Z |
Descriptor | Serine/threonine-protein kinase PLK4, CHLORIDE ION, SULFATE ION, ... (4 entities in total) |
Functional Keywords | ser/thr kinase, cell cycle |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole: O00444 |
Total number of polymer chains | 2 |
Total formula weight | 53183.08 |
Authors | |
Primary citation | Park, S.Y.,Park, J.E.,Kim, T.S.,Kim, J.H.,Kwak, M.J.,Ku, B.,Tian, L.,Murugan, R.N.,Ahn, M.,Komiya, S.,Hojo, H.,Kim, N.H.,Kim, B.Y.,Bang, J.K.,Erikson, R.L.,Lee, K.W.,Kim, S.J.,Oh, B.H.,Yang, W.,Lee, K.S. Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis. Nat.Struct.Mol.Biol., 21:696-703, 2014 Cited by PubMed: 24997597DOI: 10.1038/nsmb.2846 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.601 Å) |
Structure validation
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