4N9J

Crystal structure of the cryptic polo box domain of human Plk4

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004674	molecular_function	protein serine/threonine kinase activity
A	0005814	cellular_component	centriole
A	0006468	biological_process	protein phosphorylation
A	0007099	biological_process	centriole replication
B	0004674	molecular_function	protein serine/threonine kinase activity
B	0005814	cellular_component	centriole
B	0006468	biological_process	protein phosphorylation
B	0007099	biological_process	centriole replication

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 901

Chain	Residue
A	ARG672
A	ARG672

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 902

Chain	Residue
A	ASN652
A	GLY653
A	THR667
A	HOH1028
B	THR793

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site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL B 901

Chain	Residue
B	ARG603
B	LYS605

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site_id	AC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL B 902

Chain	Residue
B	ARG598

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site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL B 903

Chain	Residue
B	TYR673
B	LYS681
B	TYR682

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site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL B 904

Chain	Residue
B	ARG672
B	ARG672

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site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL B 905

Chain	Residue
B	HIS597
B	ARG794

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site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 B 906

Chain	Residue
A	GLN604
B	GLY653
B	THR667
B	HOH1039

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	226
Details	Domain: {"description":"Cryptic POLO box 1 (CPB1)","evidences":[{"source":"PROSITE-ProRule","id":"PRU01328","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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