4MWT

Crystal structure of human PPCA (trigonal crystal form 2)

Summary for 4MWT

Entry DOI	10.2210/pdb4mwt/pdb
Related	1IVY 4MWS
Descriptor	Lysosomal protective protein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	cathepsin a, glycoprotein, serine protease, carboxypeptidase, protective protein, n-linked glycosylation, proteolytically activated form, lysosomal enzyme, hydrolase
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	98561.33
Authors	Kolli, N.,Garman, S.C. (deposition date: 2013-09-25, release date: 2014-03-12, Last modification date: 2020-07-29)
Primary citation	Kolli, N.,Garman, S.C. Proteolytic activation of human cathepsin A. J.Biol.Chem., 289:11592-11600, 2014 Cited by PubMed: 24599961 DOI: 10.1074/jbc.M113.524280 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.85 Å)

Structure validation