4MUQ

Crystal Structure of Vancomycin Resistance D,D-dipeptidase VanXYg in complex with D-Ala-D-Ala phosphinate analog

4MUQ の概要

• エントリーDOI: 10.2210/pdb4muq/pdb
• 関連するPDBエントリー: 4F78 4MUR 4MUS 4MUT 4OAK
• 分子名称: D,D-dipeptidase/D,D-carboxypeptidase, ZINC ION, (2R)-3-[(R)-[(1R)-1-aminoethyl](hydroxy)phosphoryl]-2-methylpropanoic acid, ... (8 entities in total)
• 機能のキーワード: center for structural genomics of infectious diseases, csgid, national institute of allergy and infectious diseases, niaid, alpha+beta protein, metallopeptidase, hedgehog/dd-peptidase fold, merops m15b subfamily, zn2+-dependent d, d-dipeptidase, vancomycin resistance, antibiotic resistance, hydrolase
• 由来する生物種: Enterococcus faecalis
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 32829.34

構造登録者

Stogios, P.J.,Evdokimova, E.,Meziane-Cherif, D.,Di Leo, R.,Yim, V.,Courvalin, P.,Savchenko, A.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2013-09-23, 公開日: 2013-10-09, 最終更新日: 2023-09-20)

• 主引用文献: Meziane-Cherif, D.,Stogios, P.J.,Evdokimova, E.,Savchenko, A.,Courvalin, P.; Structural basis for the evolution of vancomycin resistance D,D-peptidases.; Proc.Natl.Acad.Sci.USA, 111:5872-5877, 2014; PubMed: 24711382; DOI: 10.1073/pnas.1402259111

実験手法

X-RAY DIFFRACTION (1.364 Å)