4F78

Crystal Structure of Vancomycin Resistance D,D-dipeptidase VanXYg

Summary for 4F78

• Entry DOI: 10.2210/pdb4f78/pdb
• Related: 4MUQ 4MUR 4MUS 4MUT 4OAK
• Descriptor: D,D-dipeptidase/D,D-carboxypeptidase, ZINC ION, CHLORIDE ION, ... (7 entities in total)
• Functional Keywords: center for structural genomics of infectious diseases, csgid, national institute of allergy and infectious diseases, niaid, alpha+beta protein, metallopeptidase, hedgehog/dd-peptidase fold, merops m15b subfamily, zn2+-dependent d, d-dipeptidase, vancomycin resistance, d-alanine-d-alanine, hydrolase
• Biological source: Enterococcus faecalis
• Total number of polymer chains: 1
• Total formula weight: 30869.83

Authors

Stogios, P.J.,Wawrzak, Z.,Evdokimova, E.,Minasov, G.,Egorova, O.,Di Leo, R.,Kudritska, M.,Yim, V.,Meziane-Cherif, D.,Courvalin, P.,Savchenko, A.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2012-05-15, release date: 2012-05-23, Last modification date: 2014-05-14)

• Primary citation: Meziane-Cherif, D.,Stogios, P.J.,Evdokimova, E.,Savchenko, A.,Courvalin, P.; Structural basis for the evolution of vancomycin resistance D,D-peptidases.; Proc.Natl.Acad.Sci.USA, 111:5872-5877, 2014; PubMed: 24711382; DOI: 10.1073/pnas.1402259111

Experimental method

X-RAY DIFFRACTION (1.95 Å)