4MSQ

Crystal structure of Schizosaccharomyces pombe AMSH-like protease sst2 catalytic domain bound to ubiquitin

Summary for 4MSQ

Entry DOI	10.2210/pdb4msq/pdb
Related	3RZU 4JXE 4MS7 4MSD 4MSJ 4MSM
Descriptor	AMSH-like protease sst2, Ubiquitin, ZINC ION, ... (6 entities in total)
Functional Keywords	ubiquitin, deubiquitination, helix-beta-helix sandwich, zinc metalloprotease, lysine 63-linked polyubiquitin, cytosol, endosome, hydrolase-protein binding complex, hydrolase/protein binding
Biological source	Schizosaccharomyces pombe (Fission yeast) More
Cellular location	Cytoplasm: Q9P371 Ubiquitin: Cytoplasm (By similarity): P0CG48
Total number of polymer chains	4
Total formula weight	63103.52
Authors	Shrestha, R.K.,Ronau, J.A.,Das, C. (deposition date: 2013-09-18, release date: 2014-06-18, Last modification date: 2024-02-28)
Primary citation	Shrestha, R.K.,Ronau, J.A.,Davies, C.W.,Guenette, R.G.,Strieter, E.R.,Paul, L.N.,Das, C. Insights into the Mechanism of Deubiquitination by JAMM Deubiquitinases from Cocrystal Structures of the Enzyme with the Substrate and Product. Biochemistry, 53:3199-3217, 2014 Cited by PubMed: 24787148 DOI: 10.1021/bi5003162 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.952 Å)

Structure validation